2. Signaling Pathways
  3. Anti-infection
  4. Parasite

Parasite

Parasite

Related Products

PDF 2.67 MB

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Parasite Isoform Specific Products:

Parasite Isoform Comparison
Cat. No. Product Name Effect Purity Chemical Structure
  • HY-123305S
    5-Hydroxymebendazole-d3
    5-Hydroxymebendazole-d3 is a deuterium labeled 5-Hydroxymebendazole. 5-Hydroxymebendazole is the one metabolite of Benzimidazoles[1].
    5-Hydroxymebendazole-d<sub>3</sub>
  • HY-113050
    2,3-Diphosphoglyceric acid
    		Inhibitor
    2,3-Diphosphoglyceric acid (2,3-DPG) is an intermediate of the glycolytic pathway. 2,3-Diphosphoglyceric acid stabilizes the deoxygenated form of hemoglobin by allosteric binding and facilitates oxygen release at tissue sites. 2, 3-diphosphoglyceric acid has antiparasitic activity. 2,3-Diphosphoglyceric acid can be used in the study of Alzheimer's disease (AD).
    2,3-Diphosphoglyceric acid
  • HY-B0827R
    Dinotefuran (Standard)
    		Inhibitor
    Dinotefuran (Standard) is the analytical standard of Dinotefuran. This product is intended for research and analytical applications.
    Dinotefuran (Standard)
  • HY-146489
    Anti-infective agent 3
    		Inhibitor
    Anti-infective agent 3 (compound 3l) shows antiparasitic activity against P. falciparum and T. brucei rhodesiense, with IC50 values of 0.47 and 0.13 μM, respectively. Anti-infective agent 3 shows antimycobacterial activity against Mycobacterium smegmatis with a MIC of 4 μg/mL.
    Anti-infective agent 3
  • HY-B0827A
    (R)-Dinotefuran
    		Inhibitor
    (R)-Dinotefuran ((R)-MTI-446), a neonicotinoid pesticide, exhibits comparative insecticidal activities (1.7-2.4 times) to typical sucking pests Aphis gossypii and Apolygus lucorum compared to racemic mixtures by inhibiting nicotinic acetylcholine receptors. (R)-Dinotefuran has a good efficacy in controlling target pests while minimizing hazard to honeybees.
    (R)-Dinotefuran
  • HY-Y0148R
    10-Hydroxydecanoic acid (Standard)
    10-Hydroxydecanoic acid (Standard) is the analytical standard of 10-Hydroxydecanoic acid. This product is intended for research and analytical applications. 10-Hydroxydecanoic acid (10-HDAA) is a saturated fatty acid derived from 10-hydroxy-trans-2-decenoic acid, which can be isolated from royal jelly. 10-Hydroxydecanoic acid exhibits various biological activities, including anti-inflammatory, insecticidal, anti-malarial, and anti-Leishmania properties, as well as enhancing antigen-specific immune responses. The anti-inflammatory effects of 10-Hydroxydecanoic acid are primarily mediated by inhibiting the activation of NF-κB and the translation of interferon regulatory factor 1 (IRF-1), which reduces the production of interleukin 6 (IL-6) and nitric oxide (NO) in inflammatory cells. Additionally, 10-Hydroxydecanoic acid alleviates neuroinflammatory responses through the p53-autophagy pathway and the p53-NLRP3 pathway. Finally, 10-Hydroxydecanoic acid enhances antigen-specific immune responses by promoting the effective uptake of antigens by microfold cells[1][2][3][4][5].
    10-Hydroxydecanoic acid (Standard)
  • HY-D0008
    Brilliant green
    		Inhibitor
    Brilliant green is a cationic dye used to color silk and wool. Brilliant green inhibits propagation of mold, intestinal parasites and fungus. Brilliant green is effective against Gram-positive bacteria.
    Brilliant green
  • HY-N8285
    Sporogen AO-1
    		Inhibitor
    Sporogen AO-1 is a fungal metabolite originally isolated from the fungusAspergillus oryzae. Sporogen AO-1 has significant antimalarial activity againstplasmodium falciparum, with an IC50 value of 1.53 μM, and also has certain cytotoxicity.
    Sporogen AO-1
  • HY-168342
    Anti-Trypanosoma cruzi agent-6
    		Inhibitor
    Anti-Trypanosoma cruzi agent-6 (Compound 8) exhibits inhibitory activity against Trypanosoma cruzi, that inhibits the epimastigote, trypomastigote and amastigote form of T. cruzi with IC50s of 24.7 µM, 1.8 µM and 1.6 µM, respectively.
    Anti-Trypanosoma cruzi agent-6
  • HY-158060
    MC2646
    		Inhibitor
    MC2646 is a potent anti-parasite agent. MC2646 induces autophagic. MC2646 activates the AMPK/TFEB pathway.
    MC2646
  • HY-N8383
    Butyrolactone V
    Butyrolactone V is a butanolide compound. Butyrolactone V shows antiplasmodial activity against Plasmodium falciparum K1 with an IC50 of 7.9 µg/ml.
    Butyrolactone V
  • HY-116021S
    Buquinolate-13C3
    		Inhibitor
    Buquinolate-13C3 is the 13C3 labeled Buquinolate. Buquinolate is a quinoline derivative, which is developed as a coccidiostat for the prevention of coccidiosis in poultry.
    Buquinolate-<sup>13</sup>C<sub>3</sub>
  • HY-B1896S
    Piperaquine-d6
    Piperaquine-d6 is the deuterium labeled Piperaquine[1]. Piperaquine is a bisquinoline antimalarial agent. Piperaquine can be used in antimalarial research in combination with Artemisinin[2][3].
    Piperaquine-d<sub>6</sub>
  • HY-N7985
    Pendulone
    		Inhibitor
    Pendulone is a isoflavanquinone with good antiplasmodial activity with an IC50 of 7.0 µM. Pendulone also has antileishmanial, antibacterial and anticancer activity.
    Pendulone
  • HY-136458
    3-ANOT
    		Inhibitor
    3-ANOT is a metabolite of Dinitolmide (a nitroamide coccidiostat commonly used in poultry production).
    3-ANOT
  • HY-121688
    Sulphenone
    		Inhibitor
    Sulphenone is a chemical that can be used for the control of mite.
    Sulphenone
  • HY-N12276
    (±)-Emodin bianthrone
    		Inhibitor
    (±)-Emodin bianthrone (compound 10), a natural product, exhibits antimalarial, antitubercular and ntifungal activities.
    (±)-Emodin bianthrone
  • HY-114800
    Soporidine
    Soporidine is an antagonist of germination of the parasitic plant Striga hermonthica. Soporidine specifically inhibits a S. hermonthica strigolactone receptor and inhibits the parasite's germination. Soporidine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Soporidine
  • HY-N10381
    Zedoalactone B
    		Inhibitor
    Zedoalactone B is an anti-Babesial agent with an IC50 of 1.6 μg/mL against Babesia gibsoni. Zedoalactone B inhibits NO production with an IC50 of 23.8 μM.
    Zedoalactone B
  • HY-155130
    Antimalarial agent 31
    		Inhibitor
    Antimalarial agent 31 (compound 7k) is an orally active Plasmodium falciparum aspartic protease plasmepsin X (PMX) inhibitor.
    Antimalarial agent 31
Parasite Isoform Comparison

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.